$ 9.00 · 4.8 (293) · In stock
The literature on pharmacologic treatments for postural orthostatic tachycardia syndrome (POTS) is inconsistent and unstandardized. Therefore, we aimed to evaluate choices in pharmacologic treatment options for POTS and the challenges encountered in the studies. We searched numerous databases like PubMed, Scopus, Embase, Web of Science, and Google Scholar for literature published before April 8, 2023. The search was done to retrieve potential peer-reviewed articles that explored drug therapy in POTS. Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were used to conduct the systematic review. Of the 421 potential articles assessed, 17 met the inclusion criteria. Results demonstrated that pharmacologic treatment options for POTS were effective in reducing symptoms of POTS, but most of the studies were underpowered. Several were terminated due to various reasons. Midodrine ivabradine, bisoprolol, fludrocortisone, droxidopa, desmopressin, propranolol, modafinil, methylphenidate, and melatonin have been studied with positive impact but sample sizes that were low in the range of 10-50 subjects. Therefore, we concluded the treatment options effectively improve symptoms of POTS and increase orthostatic tolerance, but more evidence is needed as most studies had a low sample size and thus are underpowered.
Impaired Endothelial Function in Patients With Postural Tachycardia Syndrome
Understanding and Managing Postural Orthostatic Tachycardia Syndrome
Postacute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 Infection: A State-of-the-Art Review - ScienceDirect
Understanding and Managing Postural Orthostatic Tachycardia Syndrome
PDF) Droxidopa in the Treatment of Postural Orthostatic Tachycardia Syndrome
Vaccines, Free Full-Text
Distinct Hemodynamic Responses That Culminate With Postural Orthostatic Tachycardia Syndrome - ScienceDirect
PDF) Role of NASA 10-minute Lean Test in diagnosing postural orthostatic tachycardia syndrome: a preliminary study in young population
2015 ACC/AHA/HRS Guideline for the Management of Adult Patients With Supraventricular Tachycardia: Executive Summary
PDF) Randomized Trial of Ivabradine in Patients With Hyperadrenergic Postural Orthostatic Tachycardia Syndrome